Explore the principles of evidence-based medicine, including critical appraisal, clinical decision-making, and the latest research in emergency and acute care. Our posts help clinicians interpret evidence, apply it to practice, and improve patient outcomes with a scientific approach.
It’s that time of year again when the Trauma Care UK conference comes around and I get to talk about 10 interesting trauma papers from the last 12 months or […]
Top 10 Trauma Papers for Trauma UK conference. 2020-2021. St Emyln’s Read More
I remember back at the beginning of the pandemic when we were seeing lots of patients arriving in the ED in extremis. The now familiar picture of the deeply hypoxic
JC: Non-invasive ventilation for COVID 19 patients. The Recovery RS trial. St Emlyn’s Read More
Back in March we reported on a pre-print trial of thromboprophylaxis of ICU patients. The results suggested that there was no benefit for therapeutic dose anticoagulation in COVID19 as a prophylactic strategy for
JC: Thromboprophylaxis for the non ICU hospitalised COVID-19 patient. St Emlyn’s Read More
A quick update on an TTM2 trial published in the NEJM last month. As part of the chain of survival it’s important to optimise the post resuscitation phase, primarily to
JC: The TTM2 trial. Normothermia or hypothermia post cardiac arrest. Read More
We’ve reported on the RECOVERY trial several times already on the blog. It stands out as the most important trial of therapeutics in hospitalised patients with COVID19. In the last
REGN monoclonal antibodies work in selected hospitalised COVID-19 patients. St Emlyn’s Read More
Our regular round up of the blog highlights in podcast form as hosted by Ian and Simon.
Podcast – May 2021 Monthly Round Up Read More
We’ve reported on the RECOVERY trial several times already on the blog. It stands out as the most important trial of therapeutics in hospitalised patients with COVID19. This week the
JC: Aspirin is not effective for hospitalised COVID19 patients. St Emlyn’s Read More
I’ve been reflecting on why there is disagreement about how influential new evidence is to clinical practice in the last year or so. COVID-19 has shown that the thresholds for
Bayes and Belief: How pre-review belief influences critical appraisal. St Emlyn’s Read More
