Explore the principles of evidence-based medicine, including critical appraisal, clinical decision-making, and the latest research in emergency and acute care. Our posts help clinicians interpret evidence, apply it to practice, and improve patient outcomes with a scientific approach.
This article reviews a recent study on the use of Tranexamic Acid (TXA) in traumatic brain injury (TBI) patients with intracranial hemorrhage (ICH), focusing on prehospital care.
2g or 1+1g Tranexamic Acid (TXA) in traumatic brain injury? Read More
A Critical Appraisal Nugget about Positive and Negative Predictive Value and their use when interpreting diagnostic tests.
Podcast – Positive and Negative Predictive Values: Critical Appraisal Nugget 11 Read More
A critical appraisal of a paper about feasibility, safety and impact of pre hospital zone 1 REBOA on exsanguinating peri-arrest trauma patients
Journal Club on the impact of the MACS score in emergency medicine (systematic review). Learn how this tool improves diagnosis and patient outcomes while optimising hospital resources.”FOAMed
Systematic review of the Manchester Acute Coronary Scores. Read More
This secondary analysis of the DOSE VF trial highlights double sequential external defibrillation (DSED) as a superior strategy over standard and vector change defibrillation for refractory ventricular fibrillation (RVF)
Does the outcome from refractory VF differ from recurrent VF in DOSE-VF patients? Read More
This study in the Journal of Trauma Acute Care Surgery shows that emergency department (ED) intubation for patients needing urgent haemorrhage control surgery is linked to higher mortality and complications. Prioritising rapid resuscitation and OR transfer over ED intubation may improve outcomes. Further prospective research is needed
Risky intubations in the Emergency Department Read More
Bougie use in the Emergency Department – a meta analysis
Bougie use in tracheal intubation Read More
Greg Yates reviews for Journal Club a review of a JAMA paper on elderly deaths associated with long overnight waits on an ED trolley.
Are long waits in A&E lethal for elderly patients? Read More
