Tom Roberts and Dan Horner discuss the SHED study of adults presenting with acute headache. The article and podcast examine CT timing, the Ottawa SAH rule and lumbar puncture, including why observational evidence and the distinction between aneurysmal and non-aneurysmal bleeding matter when considering changes to practice.
The Subarachnoid Haemorrhage in the Emergency Department (SHED) Study Read More
Semi-structured interviews are a great way to get the really rich data we need to understand something in greater depth. They allow us to ask ‘why?’ as well as just ‘what?’, ‘who?’ and ‘when?’.
Semi Structured Interviews (CAN9) Read More
A 2021 appraisal of the Canadian TIA score’s prospective validation and comparison with ABCD scores. It explores seven-day stroke risk, the need for validation in other settings and why better prediction only helps when local services can act on the result.
JC: Canadian TIA risk score. St Emlyn’s Read More
A September 2020 appraisal of REMAP-CAP’s hydrocortisone results in critically ill patients with COVID-19. Dan Horner and Simon Carley explain adaptive trials, Bayesian analysis and organ support outcomes, weighing the findings against early stopping, treatment crossover and the wider corticosteroid evidence.
The ‘Roid’ to Recovery? REMAP-CAP @ St Emlyn’s Read More
A selection of COVID-19 papers reviewed for emergency clinicians in August 2020. The Leicester team examines aerosol transmission, CPAP, surgical and cardiac complications, thromboprophylaxis, staff mental health and frailty, distinguishing early signals and expert consensus from stronger evidence.
Covid-19 Journal Club: The Director’s Cut #6 Read More
An August 2020 appraisal of hydroxychloroquine after household or occupational exposure to COVID-19. It examines a placebo-controlled trial’s lack of a clear benefit, adverse effects and the uncertainty introduced by remote recruitment and outcomes based largely on self-reported symptoms.
JC: Does post exposure prophylaxis (with HCQ) work in Covid-19? Read More
An early June 2020 response to RECOVERY’s announcement that hydroxychloroquine had not shown benefit in hospitalised patients with COVID-19. Simon Carley explains the platform trial design and why the limited information released at that stage still required a full critical appraisal.
The RECOVERY platform trial: No benefit to Hydroxychloroquine in Covid-19. St Emlyn’s Read More
The 2019–2020 St Emlyn’s journal club book brings together more than 30 critical appraisals, with links to downloadable editions. The introduction encourages readers to compare interpretations, revisit disputed studies such as CRASH-3 and use the collection to start evidence-based discussions with colleagues.
JC: Journal club book for 2019-2020 published. #FOAMed Read More
