Tag Archive: critical appraisal

Is cMyC the new troponin?

Anyone who reads the news is likely to have seen the recent paper in Circulation evaluating a new biomarker of acute coronary syndromes: cardiac myosin binding protein C (cMyC) . This paper has been covered by the BBC, the Telegraph…
Read more

JC: Oxygen in ACS. A fuss about nothing? The DETO2X Trial at St.Emlyn’s

DETO2X-SWEDEHEART sounds like a new low-carb, high-alkali, So-Cal diet plan but it is actually a trial exploring the affect of oxygen on mortality in patients with a suspected acute coronary syndrome (ACS). There is a striking similarity tenuous link between…
Read more

JC: The VTE and Major Trauma. St.Emlyn’s

All good EM/CC clinicians know that venous thrombo embolism (VTE) is a potential complication of traumatic injury. The immobilisation and haematological changes associated with signficant injury are reasonably well described. Additionally there are controversies over the use of drugs such…
Read more

10+1 papers for the Northern Emergency Medicine conference. St.Emlyn’s

I had the honour to speak at the very first Northern Emergency Medicine conference back in 2014 (I think). I had a fantastic time and met so many enthusiastic and superb emergency clinicians. This year I’m lucky enough to be…
Read more

JC: Salt or Sugar? Hypertonic saline for head injury at St.Emlyn’s.

‘Why did you give Mannitol?’ asked the Registrar. ‘Hypertonic saline was the standard of care for head injury at St.Elsewhere and I was told it reduced mortality’. OK, so that’s a paraphrased recollection from some time ago. Our patient had…
Read more

Translate »