Journal Club

Musings form the evidence based journal club at St Emlyns

JC: Does earlier TXA save lives? St.Emlyn’s

Administration of tranexamic acid (TXA) is integral part of the management for major trauma patients in the UK. It is deemed such an important aspect that its administration is used as a quality indicator to benchmark major trauma centres across…
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Is cMyC the new troponin?

Anyone who reads the news is likely to have seen the recent paper in Circulation evaluating a new biomarker of acute coronary syndromes: cardiac myosin binding protein C (cMyC) . This paper has been covered by the BBC, the Telegraph…
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JC: Oxygen in ACS. A fuss about nothing? The DETO2X Trial at St.Emlyn’s

DETO2X-SWEDEHEART sounds like a new low-carb, high-alkali, So-Cal diet plan but it is actually a trial exploring the affect of oxygen on mortality in patients with a suspected acute coronary syndrome (ACS). There is a striking similarity tenuous link between…
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JC: The VTE and Major Trauma. St.Emlyn’s

All good EM/CC clinicians know that venous thrombo embolism (VTE) is a potential complication of traumatic injury. The immobilisation and haematological changes associated with signficant injury are reasonably well described. Additionally there are controversies over the use of drugs such…
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Mike Charlesworth and Lee Feddy: ‘Predatory publishers’ – time for a re-think?

Imagine that you are a foundation doctor (PGY 1-2), and you have written a case report during your general surgery rotation. Your supervisor has approved the manuscript and delegated the responsibility of submission to you. You decide to start with…
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